Efficient drug delivery using SiO 2 -layered double hydroxide nanocomposites

Layered double hydroxide nanomaterials as potential cellular drug delivery agents*

This paper briefly reviews the recent progress in using layered double hydroxide (LDH) nanomaterials as cellular delivery agents. The advantages of LDHs as cellular delivery agents are summarized, and the processes of interaction/de-intercalation of anionic drugs (genes) into/from LDH nanoparticles are discussed. Then the cellular delivery of LDH-drug (gene) nanohybrids and subsequent intracell...

Layered Double Hydroxide-Based Nanocarriers for Drug Delivery

Biocompatible clay materials have attracted particular attention as the efficient drug delivery systems (DDS). In this article, we review developments in the use of layered double hydroxides (LDHs) for controlled drug release and delivery. We show how advances in the ability to synthesize intercalated structures have a significant influence on the development of new applications of these materi...

Amine-functionalized SiO2 nanodot-coated layered double hydroxide nanocomposites for enhanced gene delivery

Biological Application of Layered Double Hydroxides in Drug Delivery Systems

This review focuses on the extensive study of different layered double hydroxides (LDHs)nanostructures and also their biological and physicochemical (in vitro) properties to encapsulateand deliver drugs with a recognized pharmacokinetic profile in a sustained/modified manner forbetter remedial efficacy contrasted to the corresponding conventional treatments using different<br ...

Layered double hydroxide nanocomposite for drug delivery systems; bio-distribution, toxicity and drug activity enhancement

The production of layered double hydroxide(LDH) nanocomposite as an alternative drug delivery system against various ailments is on the increase. Their toxicity potential is usually dose and time dependent with particle sizes, shapes and surface charge playing some role both in the in vitro and in vivo studies. The reticular endothelial system of especially the liver and spleen were shown to se...